Welcome to the Ted and Eileen Pasquarello Tissue Bank
ATTENTION:
Pasquarello Tissue Bank has moved to DA-L181A on 06/18/2019.
The Pasquarello Tissue Bank receives, processes, banks, and distributes research samples from Protocol 01-206: Tissue and Data Collection for Research Studies in Patients with Hematologic Malignancies, Bone Marrow Disorders and Normal Donors. The PTB also supports banking of blood, bone marrow and other tissues for many other research protocols in patients undergoing hematopoietic stem cell transplantation, immune therapies and cellular therapies. FreezerWorks and caTissue are the Specimen Inventory databases which are used to track the de-identified, bar-coded samples. We have six Biological Safety cabinets. We have on site six vapor phase LN2 tanks, along with eight -80º C mechanical freezers for storage of research specimens. This has the capacity for over 300,000 vials of mononuclear cells stored at -190°C and 170,000 vials of other specimen types stored at -80°C or -30°C.
Pasquarello Tissue Bank banked samples have been used in the following examples:
Pasquarello Tissue Bank has moved to DA-L181A on 06/18/2019.
The Pasquarello Tissue Bank receives, processes, banks, and distributes research samples from Protocol 01-206: Tissue and Data Collection for Research Studies in Patients with Hematologic Malignancies, Bone Marrow Disorders and Normal Donors. The PTB also supports banking of blood, bone marrow and other tissues for many other research protocols in patients undergoing hematopoietic stem cell transplantation, immune therapies and cellular therapies. FreezerWorks and caTissue are the Specimen Inventory databases which are used to track the de-identified, bar-coded samples. We have six Biological Safety cabinets. We have on site six vapor phase LN2 tanks, along with eight -80º C mechanical freezers for storage of research specimens. This has the capacity for over 300,000 vials of mononuclear cells stored at -190°C and 170,000 vials of other specimen types stored at -80°C or -30°C.
Pasquarello Tissue Bank banked samples have been used in the following examples:
- Monitor reconstitution of various immune cells after stem cell transplantation.
- Monitor immune response to cancer vaccines.
- Identify and validate predictive biomarkers.
- Monitor T-cell diversity after stem cell transplantation and following immunotherapy.
- Measure levels of cytokines such as BAFF, IL-2, GM-CSF.
- Identify new oncogenes in leukemia.
- Monitor minimal residual disease.
- High throughput DNA sequencing of T-cell and B-cell receptors to evaluate repertoire diversity after transplantation.
- Whole genome sequencing of various leukemias.